Risk factors for adverse outcomes of percutaneous endoscopic gastrostomy

Author:

Zharikov Yu. O.1ORCID,Gurtsiev M. Kh.2ORCID,Samsonova M. D.1ORCID,Ter-Akopyan K. A.1ORCID,Yartsev P. A.3ORCID

Affiliation:

1. Sechenov First Moscow State Medical University

2. N.V. Sklifosovskii Research Institute for Emergency Medicine

3. N.V. Sklifosovskii Research Institute for Emergency Medicine; Penza Institute of Advanced Medical Training, a branch of the Russian Medical Academy of Continuing Professional Education

Abstract

Introduction. Presently, percutaneous endoscopic gastrostomy is considered to be the operation of choice when long-term enteral feeding in dysphagia syndrome is required. The technique is characterized by low incidence of early and long-term complications due to low traumatic access and operation time. Aim of the work was to assess the risk predictors of percutaneous endoscopic gastrostomy complications and their significance for the postoperative period. Materials and methods. We searched publications and analyzed literature sources using PubMed and MedLine databases and Cochrane Library and elibrary.ru scientific libraries mainly for the last ten years. The search was performed using a set of key words: percutaneous endoscopic gastrostomy, dysphagia syndrome, postoperative complications, risk factors. Results and discussion. The leading and most studied predictors of early and long-term postoperative period complications after gastrostomy are hypoalbuminemia, uncompensated diabetes mellitus, thrombocytopenia, elevated levels of C-reactive protein, Charlson's comorbidity index (4 points or higher), antiaggregant and anticoagulant therapy, morphoconstitutional features of patients. Conclusion. Data analysis has shown that percutaneous endoscopic gastrostomy at high patient flow and gastropectomy supplementation with gastropexy is practically safe and effective if the selection criteria for the operation are observed taking into account the general condition, risk factors and exclusion of absolute contraindications.

Publisher

Ural State Medical University

Subject

General Medicine

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