Dynamics of changes in the microflora of the oral fluid after the removal of lower wisdom teeth against the background of antibiotic therapy and phage therapy

Author:

Oleinik N. A.1ORCID,Fomichev E. V.1ORCID,Yakovlev A. T.2ORCID,Kirpichnikov M. V.1ORCID,Khimich I. V.1ORCID,Madatkhanova A. A.1ORCID,Zlenko A. S.1ORCID,Serbin A. S.1,Aleshanov K. A.3

Affiliation:

1. Volgograd State Medical University

2. FKUZ Volgograd Research Anti-Plague Institute

3. Мedical dental center on Zelenogradskaya Co.

Abstract

The purpose of our study was to study the effectiveness of the drug «Sextafag» as a therapeutic and prophylactic agent after the removal of impacted lower third molars.Recently, there has been a large number of patients with antibiotic resistance, so it is to find an alternative to traditional antibiotic therapy. This article examines the qualitative and quantitative composition of the oral microbiota after removal of impacted lower wisdom teeth. We studied the dynamics of changes in microflora during antibacterial treatment and phage therapy. The data obtained confirm the clinical and bacteriological effectiveness of oral phage therapy for inflammatory diseases in dental practice and can serve as the basis for the development of a new algorithm for the use of bacteriophages in the treatment of purulent-inflammatory diseases of the oral cavity.

Publisher

Alfmed LLC

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