Measurement of Myocardial Blood Flow in Animals and Man by Selective Injection of Radioactive Inert Gas into the Coronary Arteries

Author:

ROSS RICHARD S.1,UEDA KEIJI1,LICHTLEN PAUL R.1,REES J. RUSSELL1,Redden Redden1,Kaelber Christa1

Affiliation:

1. Departments of Medicine and Radiology, The Johns Hopkins University School of Medicine and The Johns Hopkins Hospital, Baltimore, Maryland

Abstract

1. Human myocardial blood flow has been measured by the determination of precordial radioactivity after the injection of solutions of radioactive gas directly into the coronary arteries following coronary arteriography. 2. The accuracy of radioactive gas measurements has been established in dog experiments by comparison with coronary blood flow simultaneously measured by rotameter. 3. This method has two major advantages over the existing methods of measuring human myocardial blood flow. Firstly, the right and left coronary circulations can be studied separately, this being the only method whereby the right circulation can be studied in man. Secondly, anatomical and physiological correlations are readily available as arteriography is an essential feature of the method.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference22 articles.

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2. Measurement of coronary blood flow by the nitrous oxide method;ECKENHOFF J. E.;Am. J. Physiol.,1948

3. Measurement of organ blood flow without blood sampling, (abstr.) J;CONN H. L.;Clin. Invest.,1955

4. LEWIS B. M. SOKOLOFF L. WENTZ W. B. WECHSLER R. L. AND KETY S. S.: Determination of cerebral blood flow using radioactive krypton (abstr.) Federation Proc. 14: 92 1955.

5. The Cerebral Blood Flow in Man Determined by the Use of Radioactive Krypton

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