1. From Department of Medicine (X.Q.L., Y.F.S., M.C.S., H.Q.C., J.M., G.W., K.L.P., S.M.E., J.C.), School of Pharmacology (Y.F.S., J.M., G.W., S.M.E.), Department of Pediatrics (M.Q.Y.), and Department of Pathology (A.R., H.C.P.), University of California at San Diego, and Department of Pathology, University of Pittsburgh, Pittsburgh, Pa (C.Y.W.).