Meet the Novel Players in Hypertensive Kidney Disease: Septin4 and SIRT2

Author:

Dikalov Sergey1ORCID,Kirabo Annet1ORCID

Affiliation:

1. Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference15 articles.

1. Centers for Disease Control and Prevention. Hypertension cascade: hypertension prevalence treatment and control estimates among U.S. Adults aged 18 years and older applying the criteria from the american college of cardiology and American heart association’s 2017 hypertension guideline—NHANES 2015–2018. Atlanta GA: U.S. Department of health and human services; 2021. Accessed March 12 2021. https://millionhearts.hhs.gov/data-reports/hypertension-prevalence.html

2. Prevention CfDCa. Chronic kidney disease in the United States 2021. Services UDoHaH; 2021. https://www.cdc.gov/kidneydisease/publications-resources/CKD-national-facts.html

3. Hypertensive Kidney Injury and the Progression of Chronic Kidney Disease

4. Deacetylation of Septin4 by SIRT2 (Silent Mating Type Information Regulation 2 Homolog-2) Mitigates Damaging of Hypertensive Nephropathy

5. Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration

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