1. From the Department of Medicine (E.M., I.R.S., D.M.H., M.P., N.O.R., S.T., P.H., M.W.S., F.K.), the Diabetes and Obesity Center of Excellence (I.R.S., N.O.R., S.T., P.H., M.W.S., F.K.), and the Fred Hutchinson Cancer Research Center (D.M.H.), University of Washington, Seattle.