1. From the Departments of Internal Medicine and Molecular Science (N.O., S.K., T.F., T.N., H.N., M. Kumada, K.O., Y.O., H.N., K.K., N.M., A.N., H.K., H.H., Y.M.) and Geriatric Medicine (M.O., N.K., M. Kaibe, H.R., T.O.), Graduate School of Medicine, Osaka University, Osaka, Japan.