Author:
Brott T,Thalinger K,Hertzberg V
Abstract
To better define the etiologic importance of hypertension for spontaneous intracerebral hemorrhage, hospital records were studied for all patients sustaining intracerebral hemorrhage during 1982 in the Cincinnati metropolitan area. Hypertension pre-dating the hemorrhage was present in 45% (69 of 154), as determined by history. A more inclusive definition of hypertension, combining those with a positive history with those found to have left ventricular hypertrophy by electrocardiogram or cardiomegaly by chest radiography, applied in 56% (87 of 154). The cases were compared to controls with and without hypertension derived from the NHANES II study of blood pressure (n = 16,204) to determine relative risk. For the presence of hypertension by history, the relative risk of intracerebral hemorrhage was 3.9 (95% confidence interval, 2.7 to 5.7). For the inclusive definition of hypertension, the relative risk was 5.4 (3.7 to 7.9). Relative risk was also determined for hypertension in blacks (= 4.4), age greater than 70 (= 7), prior cerebral infarction (= 22), and diabetes (= 3). We conclude that the term "hypertensive hemorrhage" should be used very selectively, particularly in whites, and propose that hypertension be viewed as one of several important risk factors for spontaneous intracerebral hemorrhage.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology
Reference35 articles.
1. Barnett HIM: Intracranial hemorrhage. In Textbook of Medicine. Wyngarden JB Smith LH (eds). Philadelphia: WB Saunders pp 2108-2111 1985
2. Mohr JP: Cerebrovascular disease. In: Principles of Internal Medicine. Braundwald W Isselbacher KF Martin JB Wilson JD (eds). New York: McGraw-Hill pp 2050-2052 1983
3. Preziosi TJ Moses H: Cerebrovascular Disorders. In: The Principles and Practice of Medicine. Harvey AM Johns RJ McKusick VA Owens AH Ross RS (eds). Norwalk: Appleton-Century-Crofts pp 1290-1293 1984
4. Primary intracerebral hemorrhage;McKissock W;The Lancet,1961
5. Hypertensive Brain Hemorrhage
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