Honoring 50 Years of Clinical Heart Transplantation in Circulation

Author:

Stehlik Josef1,Kobashigawa Jon2,Hunt Sharon A.3,Reichenspurner Hermann4,Kirklin James K.5

Affiliation:

1. Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City (J.S.)

2. Cedars-Sinai Heart Institute, Los Angeles, CA (J.K.)

3. Division of Cardiovascular Medicine, Stanford University, CA (S.A.H.)

4. Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany (H.R.)

5. Division of Cardiothoracic Surgery, University of Alabama at Birmingham (J.K.K.).

Abstract

Heart transplantation has become a standard therapy option for advanced heart failure. The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplantation logistics, infection control, and long-term graft surveillance. This review explores the key milestones of the past 50 years of heart transplantation and discusses current challenges and promising innovations on the clinical horizon.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference104 articles.

1. The transplantation of veins and organs;Carrel A;Am Med,1905

2. Practical methods of homologous cardiac transplantation.;Webb WR;J Thorac Surg,1959

3. Homologous transplantation of the canine heart.;Golberg M;J Int Coll Surg,1958

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