1. From Hatter Cardiovascular Institute, University College London, United Kingdom (D.J.H., D.M.Y.); Barts Heart Centre, St Bartholomew’s Hospital, London, United Kingdom (D.J.H); National Heart Research Institute Singapore, National Heart Centre Singapore (D.J.H); Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore (D.J.H); and Yong Loo Lin School of Medicine, National University Singapore (D.J.H).