Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody

Author:

Arslan Fatih1,Smeets Mirjam B.1,O'Neill Luke A.J.1,Keogh Brian1,McGuirk Peter1,Timmers Leo1,Tersteeg Claudia1,Hoefer Imo E.1,Doevendans Pieter A.1,Pasterkamp Gerard1,de Kleijn Dominique P.V.1

Affiliation:

1. From the Laboratory of Experimental Cardiology, University Medical Center Utrecht (F.A., M.B.S., L.T., C.T., I.E.H., P.A.D., G.P., D.P.V.d.K.), and Interuniversity Cardiology Institute of the Netherlands (F.A., P.A.D., G.P., D.P.V.d.K.), Utrecht, the Netherlands; School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland (L.A.J.O.); and Opsona Therapeutics Ltd, Trinity Centre for Health Sciences, St James Hospital, Dublin 8, Ireland (B.K., P.M.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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