1. From the Department of Cardiology (M.S., P.S., I.A., C.B.), University of Freiburg, Germany; Department of Clinical Pharmacology (G.M., I.A., N.M., D.K., D.F.), Royal College of Surgeons in Ireland, Dublin; Department of Biochemistry and Biocenter Oulu (J.Y.), University of Oulu, Finland; and Baker Heart Research Institute (N.B., Y.C.C., C.E.H., K.P.), Melbourne, Australia.