1. From the Departments of Biochemistry (X.W., E.B., S.H.-A., C.F.-P.) and Physiology (A.T., Z.K.), Mazankowski Alberta Heart Institute (Z.K., C.F.-P.), Cardiovascular Research Group (Z.K., C.F.-P.), and Faculty of Medicine and Dentistry (X.W., E.B., S.H.-A., C.F.-P.), University of Alberta, Edmonton, Alberta, Canada.