Decrease of Serum Cholesterol in Rabbits Following Chloroform Inhalation and as Diurnal Variation

Author:

FEDOROFF M. ELAINE1,ALTSCHUL R.1

Affiliation:

1. Department of Anatomy and Laboratory of Gerontology, University of Saskatchewan, Saskatoon, Canada

Abstract

Normal rabbits were exposed to single, subanesthetitizing doses of chloroform vapors and a regular decrease in their total serum cholesterol was found. In rabbits with abnormally high serum cholesterol levels, however, no consistent changes were observed. In control experiments it was found that in the normal rabbit there is a diurnal variation in serum cholesterol, with lowest values around 4 p.m. No consistent changes were found in the serum cholesterol of rabbits after being submerged for brief periods in ice water.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference9 articles.

1. ALTSCHTJL R.: Selected Studies on Arteriosclerosis. Springfield 111. Charles C Thomas 1950.

2. The blood cholesterol following repeated administrations of chloroform, paraldehyde, and urethane;GRAY S. H.;J. Biol. Chem.,1930

3. The influence of chloroform and ether inhalation anesthesia on different constituents of the blood of the rabbit: m . The influence on total fatty acids, cholesterol and phosphntides;KINOSHITA T.;Chem. Abst.,1932

4. The blood cholesterol in anaesthesia

5. Montreal, Acta;SELYE H.;Inc.,1950

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