1. From the Department of Physiology and Biophysics (D.R.Z., C.S.M., M.B.), Case Western Reserve University School of Medicine, Cleveland, Ohio; Department of Molecular Cardiology (D.R.Z., M.B.), Lerner Research Institute and Department of Thoracic and Cardiovascular Surgery (R.W.S.) and Center for Anesthesiology Research (C.S.M.), Cleveland Clinic Foundation, Cleveland, Ohio. The current affiliation for Dr Stewart is the University Hospitals of Cleveland, Ohio.