1. From the Population Health Research Institute, Hamilton Health Sciences, Hamilton, Ontario, Canada (M.J.J.D., S.A.R., S.S.A., H.G., G.P.); Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital, Basel, Switzerland (M.B.); and Department of Clinical Epidemiology and Biostatistics (M.B., S.S.A., H.G., G.P.), Department of Medicine (S.S.A., H.G.), and Department of Pathology and Molecular Medicine (G.P.), McMaster University, Hamilton, Ontario, Canada.