1. From the Department of Pharmacology (S.M., N.H.P., J.M.S., K.H., R.C., A.C.N., J.H.B.), University of California San Diego, La Jolla; Department of Molecular and Cellular Biochemistry (T.G.), Markey Cancer Center, Lexington, Ky; and San Diego State University Heart Institute (R.W., C.C.G., M.A.S.), San Diego State University, Calif.