1. From the Cancer Research UK London Research Institute (S.A., N.K., R.H.A.), Vascular Development Laboratory, London, UK; Max-Planck-Institute of Biochemistry (R.F.), Department of Molecular Medicine, Martinsried, Germany; Max-Planck-Institute for Molecular Biomedicine (R.H.A.), Department of Tissue Morphogenesis, and University of Münster, Faculty of Medicine, Münster, Germany.