COVID-19 and the Heart

Author:

Akhmerov Akbarshakh1,Marbán Eduardo1ORCID

Affiliation:

1. From the Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA.

Abstract

Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference98 articles.

1. World Health Organization. Coronavirus disease 2019 (COVID-19): situation reports. Available at: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/. Accessed April 3 2020.

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3. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China [published online March 3, 2020].;Ruan Q;Intensive Care Med,2020

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