1. From the Department of Molecular Biology (E.R.P., B.A.J., A.B.A., Y.-J.N., E.N.O.) and Department of Pathology (E.S.), University of Texas Southwestern Medical Center, Dallas, TX; Washington University Center for Pharmacogenomics (S.J.M., G.W.D.), St Louis, MO; and MiRagen Therapeutics (E.v.R.), Boulder, CO.