1. From the Department of Medicine, Department of Microbiology, Immunology, and Molecular Genetics (P.S.G., M.J.C., J.P., A.J.L.), Department of Human Genetics (P.S.G., M.J.C., J.P., A.J.L.), and Department of Pathology (N.M.G., T.B.-O., J.A.B.), University of California, Los Angeles; and Bristol-Myers Squibb (W.-P.Y., A.H., A.T., T.G.K.), Pharmaceutical Research Institute, Princeton, NJ.