1. From the Evans Memorial Department of Medicine (J.F.K. R.S.V., P.W.F.W., J.A.V., E.J.B.), Whitaker Cardiovascular Institute (J.F.K., I.L., J.A.V.), and Department of Preventive Medicine (R.S.V., E.J.B.), Boston University School of Medicine; Department of Epidemiology and Biostatistics (J.M.M.), Boston University School of Public Health; and the National Heart, Lung, and Blood Institute Framingham Study (M.G.L., R.S.V., P.W.F.W., D.C., J.M.M., P.S., E.J.B.), Framingham, MA.