1. From the Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, (A.M.L., E.J.T.); The Lindner Center, Ohio Heart Health Center, Cincinnati, Ohio (D.J.K.); and Centocor, Inc, Malvern, Pa (M.A.M., L.I.D., E.S.B., K.K.P., B.F., M.T.N.).