1. From the Medical Molecular Biology Unit, Institute of Child Health, University College London, UK (T.S., A.S., N.R., D.L.); the Cardiovascular Pathophysiology Research Centre, S. Maugeri Foundation, University of Ferrara, Italy (E.P., L.C., S.C., R.F.), and Department of Cystic Fibrosis, National Heart and Lung Institute, Imperial College of London, UK (R.K.).