1. From the Research Institute of Public Health (S.K., J.A.L., K.N., J.T.S.), University of Kuopio, Finland; the Research Institute of Public Health and Department of Internal Medicine (J.A.L., L.N., D.L.), University Hospital of Kuopio, Finland; Department of Neurology (J.S.), University Hospital of Kuopio and Brain Research and Rehabilitation Centre Neuron, Kuopio, Finland; and Department of Public Health and General Practice (J.T.S.), University of Kuopio, and the Jurilab Ltd, Kuopio, Finland.