Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice

Author:

Mäki Joni M.1,Räsänen Juha1,Tikkanen Hilkka1,Sormunen Raija1,Mäkikallio Kaarin1,Kivirikko Kari I.1,Soininen Raija1

Affiliation:

1. From the Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology (J.M.M., H.T., K.I.K., R. Soininen), Department of Obstetrics and Gynecology (J.R., K.M.), and Biocenter Oulu and Department of Pathology (R. Sormunen), University of Oulu, Finland.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference20 articles.

1. Lysyl oxidases: A novel multifunctional amine oxidase family

2. Biochemistry of tropoelastin

3. Collagens and collagen-related diseases

4. Steinmann B Royce PM Superti-Furga A. The Ehlers-Danlos syndrome. In: Royce PM Steinmann B eds. Connective Tissue and Its Heritable Disorders: Molecular Genetic and Medical Aspects. New York: Wiley-Liss; 1993: 351–407.

5. Cloning and characterization of a fourth human lysyl oxidase isoenzyme

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