1. From the Department of Pharmacology (H.L., P.J., C.B., T.W., U.F.), Johannes Gutenberg University, Mainz, Germany; Pharmazentrum Frankfurt (A.H., J.P.), Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany; and Department of Pathophysiology (H.L.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.