PREDICTIVE AND PROGNOSTIC SIGNIFICANCE OF PRE-TREATMENT LYMPHOCYTE COUNT IN PATIENTS WITH METASTATIC UROTHELIAL CARCINOMA TREATED WITH PLATINUM-BASED FIRST-LINE CHEMOTHERAPY

Author:

Umemoto Susumu1,Noguchi Go1,Tsutsumi Sohgo1,Kobayashi Kota1,Ousaka Kimito1,Kishida Takeshi1

Affiliation:

1. Department of Urology, Kanagawa Cancer Center

Publisher

Japanese Urological Association

Subject

Urology

Reference22 articles.

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2. 2) von der Maase H, Sengelov L, Roberts JT, Ricci S, Dogliotti L, Oliver T, Moore MJ, Zimmermann A and Arning M: Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer. J Clin Oncol, 23 (21), 4602-4608, 2005.

3. 3) Tanji N, Ozawa A, Miura N, Yanagihara Y, Sasaki T, Nishida T, Kikugawa T, Ikeda T, Ochi T, Shimamoto K, Aoki K and Yokoyama M: Long-term results of combined chemotherapy with gemcitabine and cisplatin for metastatic urothelial carcinomas. Int J Clin Oncol, 15 (4), 369-375, 2010.

4. 4) Zou W and Chen L: Inhibitory B7-family molecules in the tumor microenvironment. Nat Rev Immunol, 8 (6), 467-477, 2008.

5. 5) Motzer RJ, Escudier B, McDermott DF, George S, Hammers HJ, Srinivas S, Tykodi SS, Sosman JA, Procopio G, Plimack ER, Castellano D, Choueiri TK, Gurney H, Donskov F, Bono P, Wagstaff J, Gauler TC, Ueda T, Tomita Y, Schutz FA, Kollmannsberger C, Larkin J, Ravaud A, Simon JS, Xu LA, Waxman IM, Sharma P and CheckMate 025 Investigators: Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma. N Engl J Med, 373 (19), 1803-1813, 2015.

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