Affiliation:
1. Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208
Abstract
In Caenorhabditis elegans oocytes, kinesin-12/KLP-18 is the major force-generating motor that promotes spindle bipolarity. A combination of in vitro and in vivo approaches is used to gain insight into the mechanisms by which KLP-18 and its adaptor MESP-1 promote spindle assembly, and it is shown that KLP-18 is also continuously required to maintain bipolarity.
Publisher
American Society for Cell Biology (ASCB)
Subject
Cell Biology,Molecular Biology
Cited by
3 articles.
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