The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis-Reference-Cited by-同舟云学术

The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis

Published:2020-08-15 Issue:18 Volume:31 Page:2070-2091
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Turn Rachel E.¹²,East Michael P.³,Prekeris Rytis⁴,Kahn Richard A.¹^ORCID

Affiliation:

1. Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322

2. Biochemistry, Cell & Developmental Biology Graduate Program, Laney Graduate School, Emory University, Atlanta, GA 30307

3. Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599

4. Department of Cell and Developmental Biology, University of Colorado, Aurora, CO 80045

Abstract

The ELMOD2 gene has been linked to a number of human pathologies and encodes an ∼32 kDa protein that acts from multiple sites in mammalian cells. Knocking out the protein in fibroblasts causes defects in microtubules and cell division.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference119 articles.

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2. Knowing when to cut and run: mechanisms that control cytokinetic abscission

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4. Fast-cycling Rho GTPases

5. ADP ribosylation factor like 2 (Arl2) protein influences microtubule dynamics in breast cancer cells

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