Morphological diagnosis of nontuberculous mycobacteriosis in the surgical material of patients with pulmonary tuberculosis

Author:

Lepekha L. N.1ORCID,Krasnikova E. V.1ORCID,Tarasov R. V.2ORCID,Nikitin S. S.1ORCID

Affiliation:

1. Central Tuberculosis Research Institute

2. Central Tuberculosis Research Institute; Moscow Medical University "Reaviz"

Abstract

Objective: to analyze the results of a morphological study of the lung tissue and small airways in the surgical material of patients with a combination of tuberculoma and nontuberculous mycobacteriosis of the lungs caused by different types of pathogen.Materials and methods. A comparative retrospective histological study of the surgical material of 34 patients with a combination of LT and NM with established microbiological different types of non-tuberculous mycobacteria (NTMB) and 36 patients with LT without concomitant pathology was carried out.Results. Diagnostically significant differences in the morphological picture of TL and NM, which manifests its morphological features in areas free from foci of tuberculosis, were revealed. The features of changes in the lung tissue and small airways in patients with slow- and fast-growing types of NTMB are shown.Conclusion. The results obtained are aimed at resolving the issue of possible correction of chemotherapy in the postoperative period. 

Publisher

Reaviz Medical University

Subject

General Medicine

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