Cell technologies as a platform for personalized therapy: global challenges in oncology

Abstract

The incidence of various types of cancer is steadily increasing. It is necessary to correctly analyze and interpret statistical data, given that the quality of medical care at all its stages is characterized not by the level of morbidity, but by the mortality rate. The leading centers of the Russian Federation can apply almost all the therapy methods to treat patients. At the same time, one of the limiting factors for increasing the survival rate is the detection of diseases mainly at the late stages, which dictates the need to increase oncological alertness and the widespread introduction of early screening diagnostics into healthcare practice. The development of many new targeted drugs has led to the fact that only a few have been shown to be effective in the treatment of only certain types of tumors. The development of bone marrow transplantation contributed to the development of other directions in medicine, which proved that the hematopoietic stem cell is a platform for personalized therapy for many diseases. The article describes the problems of cell therapy implementation in the treatment of cancer patients.