Specific features of endocrine regulation of plastic processes in premature infants and children small for gestational age-Reference-Cited by-同舟云学术

Specific features of endocrine regulation of plastic processes in premature infants and children small for gestational age

Published:2023-11-14 Issue:5 Volume:68 Page:11-16
ISSN:2500-2228
Container-title:Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
language:
Short-container-title:Ross. vestn. perinatol. pediatr.

Author:

Shaydullina M. R.¹^ORCID,Mansurova A. T.²^ORCID

Affiliation:

1. Children’s Republic Clinical Hospital; Kazan State Medical University

2. Kazan State Medical University

Abstract

Low-birthweight and preterm infants have high risk of obesity and obesity-related diseases in the future. This review article identifies risk factors and endocrine biomarkers with greatest predictive value to the metabolic diseases development. Low concentrations of IGF-1 in low-birthweight children are associated with adipogenesis. Low leptin levels may be considered as a biomarker of catch-up growth. Long term programming effects of in utero exposure to leptin extend beyond infancy into early childhood. Adiponectin levels are positively correlated with obesity in early life, but not at ages older than three years. Rapid postnatal growth rate is associated with metabolic syndrome. Conclusion. Specific features of endocrine regulation of growth and dynamics of plastic processes in premature infants and SGA children are associated with excessive accumulation of adipose tissue, which can function as a mechanism for metabolic programming of distant endocrine and cardiometabolic disorders.

Publisher

The National Academy of Pediatric Science and Innovation

Subject

Pediatrics, Perinatology and Child Health

Reference52 articles.

1. Peterkova V.A., Bezlepkina O.B., Laptev D.N., Zilberman L.I., Eremina I.A. et al. Clinical guidelines «Diabetes mellitus type 2 in childhood» 2020; 68. (in Russ.) https://www.endocrincentr.ru/sites/default/files/specialists/science/clinic-recomendations/sd2_deti_07.04.2012_1.pdf / Ссылка активна на 26.07.2023.

2. Web Supplement. Evidence base. In: WHO recommendations for care of the preterm or low-birth-weight infant. Geneva: World Health Organization; 2022. https://apps.who.int/iris/bitstream/handle/10665/363697/9789240058262-eng.pdf / Ссылка активна на 26.07.2023.

3. International statistical classification of diseases and related health problems, 10th revision, Fifth edition; World Health Organization; 2016. https://apps.who.int/iris/handle/10665/246208 / Ссылка активна на 26.07.2023.

4. Hodzhaeva Z.S., Shmakov R.G., Yarygina T.A., Holin A.M., Dolgushina N.V., Kan N.E. Clinical guidelines «Insufficient growth of the fetus, requiring the provision of medical care to the mother (fetal growth retardation)», 2020; 71. (in Russ.) https://rd2rzn.ru/storage/web/source/1/mVMbBZ9ZPVgzNyy-7WiqokbYt60uEfid.pdf / Ссылка активна на 26.07.2023.

5. Blencowe H., Krasevec J., de Onis M., Black R. E., An X., Stevens G. A. et al. National, regional, and worldwide estimates of low birthweight in 2015, with trends from 2000: a systematic analysis. Lancet Global Health 2019; 7(7): e849–e860. DOI:10.1016/S2214–109X(18)30565–5