Role of deep brain stimulation (DBS) in addiction disorders

Author:

Iqbal Javed1,Mansour Mohammad Naser Mohammad2,Saboor Hafiz Abdus1,Suyambu Jenisha3,Lak Muhammad Ali4,Zeeshan Muhammad Hamayl5,Hafeez Muhammad Hassan6,Arain Mustafa5,Mehmood Maria7,Mehmood Dalia8,Ashraf Mohammad9

Affiliation:

1. School of Medicine, King Edward Medical University, Lahore, Pakistan,

2. Department of Neurosurgery, Jordan University Hospital, Amman, Jordan,

3. Department of Neurosurgery, Jonelta Foundation School of Medicine, University of Perpetual Help System Dalta, Las Pinas City, Philippines,

4. School of Medicine, Combined Military Hospitals (CMH) Lahore Medical College and Institute of Dentistry, Lahore, Pakistan,

5. School of Medicine, Dow University of Health Sciences, Karachi, Pakistan

6. School of Medicine, Shalamar Medical and Dental College, Lahore, Pakistan

7. School of Medicine, Shalamar Medical and Dental College, Lahore, Pakistan,

8. School of Medicine, Fatima Jinnah Medical University, Sir Ganga Ram Hospital, Lahore, Pakistan,

9. Wolfson School of Medicine, University of Glasgow, Scotland, United Kingdom.

Abstract

Background: Addiction disorders pose significant challenges to public health, necessitating innovative treatments. This assesses deep brain stimulation (DBS) as a potential intervention for addiction disorders. Methods: A literature review was carried out with a focus on the role of DBS in addiction disorders and its future implications in neurosurgical research. Results: The online literature shows that DBS precisely modulates certain brain regions to restore addiction-related neural circuits and promote behavioral control. Conclusion: Preclinical evidence demonstrates DBS’s potential to rebalance neural circuits associated with addiction, and early clinical trials provide encouraging outcomes in enhancing addiction-related outcomes. Ethical considerations, long-term safety, and personalized patient selection require further investigation.

Publisher

Scientific Scholar

Subject

Neurology (clinical),Surgery

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