Spinal cord diffuse midline glioma with postoperative acute swelling: A case report and review of literature

Author:

Karita Hiroki1,Tsurubuchi Takao1,Amano Taishi2,Koiso Takao1,Sakamoto Noriaki1,Ishikawa Eiichi1

Affiliation:

1. Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

2. Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Abstract

Background: H3K27-altered diffuse midline glioma (DMG) is a newly classified disease according to the 5th edition of the World Health Organization classification of the central nervous system tumors. However, little is known about its progression pattern and the timing of surgical intervention, especially regarding spinal cord lesions. Case Description: A 26-year-old man presented with rapid muscle weakness progression in both upper and lower extremities and urinary dysfunction. Magnetic resonance imaging showed diffuse swelling of the cervicothoracic spinal cord. He underwent decompressive laminectomy with expansive duroplasty and tumor biopsy. The surgical specimen revealed DMG. Immediately after surgery, deterioration of limb paresis was observed, and the patient developed respiratory failure the day after surgery. Head-and-neck computed tomography on the 7th day after surgery showed spinal cord swelling and acute obstructive hydrocephalus. Conclusion: We report a rare case of a spinal DMG with acute postoperative swelling. Neurological deterioration in patients with spinal cord DMG is often exacerbated, so it is essential to suspect DMG at an early stage based on neuroimaging, and if surgery is performed on the edematous spinal cord, further rapid swelling can occur, as in the present case.

Publisher

Scientific Scholar

Subject

Neurology (clinical),Surgery

Reference19 articles.

1. Upward transtentorial herniation, hydrocephalus, and cerebellar edema in hypertensive encephalopathy;Adamson;Neurologist,2005

2. H3F3A K27M mutations in thalamic gliomas from young adult patients;Aihara;Neuro Oncol,2014

3. Cervicothoracic syringomyelia caused by cervical spinal stenosis: Case report and literature review;Badri;Surg Neurol Int,2017

4. Syringomyelia secondary to cervical spondylosis: Case report and review of literature;Bhagavathula Venkata;J Neurosci Rural Pract,2014

5. Biopsying a spinal cord lesion: A diagnostic dilemma. Case report and review of literature;Dormegny;Neurochirurgie,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3