Immunoglobin G Sero-Dynamics Aided Host Specific Linear Epitope Identification and Differentiation of Infected from Vaccinated Hosts

Author:

Chen Xiaochun1,Li Jingzhi2,Yang Lan2,Zhou Yuxi2,Li Mengyu2,Xu Wenwen2,Qin Yixian1,Su Jia1,Zhao Wei1,Gu Chaoyi3,Sheng Shuixing4,Pan Yongfei5,Xue Qinghong1,Ma Hongwei2ORCID

Affiliation:

1. China Institute of Veterinary Drug Control, Beijing, China

2. Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, China

3. Suzhou Qiangdong Biotechnology Co. Ltd., Suzhou, China

4. Suzhou Animal Husbandry and Veterinary Station, Suzhou, China

5. Guangdong Wen’s Group Academy, Yunfu, China

Abstract

Sudden outbreaks of pandemics caused by virus, such as SARS-CoV-2, has been determined as a public health emergency of international concern. However, the development of a DIVH-compatible vaccine is time-consuming and full of uncertainty, which is unsuitable for an emergent situation like the ongoing COVID-19 pandemic.

Funder

China Veterinary Drug Administration

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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