Whole-Genome Sequence of a bla OXA-48 -Harboring Raoultella ornithinolytica Clinical Isolate from Lebanon-Reference-Cited by-同舟云学术

Whole-Genome Sequence of a bla OXA-48 -Harboring Raoultella ornithinolytica Clinical Isolate from Lebanon

Published:2016-04 Issue:4 Volume:60 Page:2548-2550
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Al-Bayssari Charbel¹²,Olaitan Abiola Olumuyiwa²^ORCID,Leangapichart Thongpan²,Okdah Liliane²,Dabboussi Fouad¹,Hamze Monzer¹,Rolain Jean-Marc²

Affiliation:

1. Laboratoire Microbiologie Santé et Environnement, Centre AZM pour la Recherche en Biotechnologie et ses Applications, Ecole Doctorale de Sciences et de Technologie, Université Libanaise, Tripoli, Lebanon

2. Aix-Marseille Université, URMITE UM 63, CNRS 7278, IRD 198, INSERM U1905, Facultés de Médecine et de Pharmacie, Marseille, France

Abstract

ABSTRACT We analyzed the whole-genome sequence of a bla OXA-48 -harboring Raoultella ornithinolytica clinical isolate from a patient in Lebanon. The size of the Raoultella ornithinolytica CMUL058 genome was 5,622,862 bp, with a G+C content of 55.7%. We deciphered all the molecular mechanisms of antibiotic resistance, and we compared our genome to other available R. ornithinolytica genomes in GenBank. The resistome consisted of 9 antibiotic resistance genes, including a plasmidic bla OXA-48 gene whose genetic organization is also described.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02773-15

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