Proteins of Mycobacterium bovis BCG Induced in the Wayne Dormancy Model

Author:

Boon Calvin1,Li Rong2,Qi Robert2,Dick Thomas1

Affiliation:

1. Mycobacterium Laboratory1 and

2. Proteomics Laboratory,2 Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore

Abstract

ABSTRACT Oxygen starvation triggers the shiftdown of the obligate aerobe Mycobacterium bovis BCG to a state of dormancy. Two-dimensional electrophoresis showed a drastic up-regulation of the α-crystallin homolog, the putative response regulator Rv3133c, and the two conserved hypothetical proteins Rv2623 and Rv2626c in dormant bacilli.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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