Dominant Negative Mutants of Human Immunodeficiency Virus Type 1 Viral Infectivity Factor (Vif) Disrupt Core-Binding Factor Beta-Vif Interaction-Reference-Cited by-同舟云学术

Dominant Negative Mutants of Human Immunodeficiency Virus Type 1 Viral Infectivity Factor (Vif) Disrupt Core-Binding Factor Beta-Vif Interaction

Published:2022-09-14 Issue:17 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Duan Sizhu¹,Yu Xin¹,Wang Chu¹,Meng Lina¹,Gai Yanxin¹,Zhou Yan¹²,Gu Tiejun¹,Yu Bin¹²,Wu Jiaxin¹²,Yu Xianghui¹²^ORCID

Affiliation:

1. National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin Province, China

2. Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, Jilin Province, China

Abstract

Antiviral therapy cannot eliminate HIV and exhibits disadvantages such as drug resistance and toxicity. Therefore, novel strategies for inhibiting viral replication in patients with HIV are urgently needed.

Funder

Science and Technology Development Project of Jilin Province

JLU | Program for Jilin University Science and Technology Innovative Research Team

National Natural Science Foundation of China

National Key Research and Development Program of China

Science and Technology Research Projects of the Education Department of Jilin Province

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00555-22

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