In Vitro Susceptibility Testing Methods for Caspofungin against Aspergillus and Fusarium Isolates-Reference-Cited by-同舟云学术

In Vitro Susceptibility Testing Methods for Caspofungin against Aspergillus and Fusarium Isolates

Published:2001-01 Issue:1 Volume:45 Page:327-330
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Arikan Sevtap¹,Lozano-Chiu Mario¹,Paetznick Victor¹,Rex John H.¹

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, Center for the Study of Emerging and Reemerging Pathogens, University of Texas Medical School, Houston, Texas 77030

Abstract

ABSTRACT We investigated the relevance of prominent reduction in turbidity macroscopically (MIC) and formation of aberrant hyphal tips microscopically (minimum effective concentration; MEC) in measuring the in vitro activity of caspofungin against Aspergillus and Fusarium . Caspofungin generated low MICs and MECs against Aspergillus , but not for Fusarium . While MICs increased inconsistently when the incubation time was prolonged, MEC appeared as a stable and potentially relevant endpoint in testing in vitro caspofungin activity.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.1.327-330.2001

Reference26 articles.

1. Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

2. Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

3. Microdilution Susceptibility Testing of Amphotericin B, Itraconazole, and Voriconazole against Clinical Isolates of Aspergillus and Fusarium Species

4. In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)

5. In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds

Cited by 183 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Fusariosis en pacientes con cáncer: serie de 13 casos y revisión de la literatura;Biomédica;2023-08-31

2. Antifungal Susceptibility of Yeasts and Filamentous Fungi by CLSI Broth Microdilution Testing;Methods in Molecular Biology;2023

3. Pharmacodynamics, Mechanisms of Action and Resistance, and Spectrum of Activity of New Antifungal Agents;Journal of Fungi;2022-08-16

4. Insecticidal and antifungal activities of Melaleuca rhaphiophylla essential oil against insects and seed-borne pathogens in stored products;Industrial Crops and Products;2022-08

5. The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin;Drugs;2021-10