Mutation in 23S rRNA Responsible for Resistance to 16-Membered Macrolides and Streptogramins in Streptococcus pneumoniae-Reference-Cited by-同舟云学术

Mutation in 23S rRNA Responsible for Resistance to 16-Membered Macrolides and Streptogramins in Streptococcus pneumoniae

Published:2001-01 Issue:1 Volume:45 Page:319-323
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Depardieu Florence¹,Courvalin Patrice¹

Affiliation:

1. Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15, France

Abstract

ABSTRACT Streptococcus pneumoniae clinical isolate BM4455 was resistant to 16-membered macrolides and to streptogramins. This unusual resistance phenotype was due to an A 2062 C ( Escherichia coli numbering) mutation in domain V of the four copies of 23S rRNA.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.1.319-323.2001

Reference31 articles.

1. Protein components of the erythromycin binding site in bacterial ribosomes.;Arevalo M. A.;J. Biol. Chem.,1988

2. Mechanism of action of spiramycin and other macrolides.;Brisson-Noel A.;J. Antimicrob. Chemother.,1988

3. Zone sizes and breakpoints for non-fastidious organisms.;Comité de l'Antibiogramme de la Société Française de Microbiologie;Clin. Microbiol. Infect.,1996

4. Characterisation of the binding of virginiamycin S to Escherichia coli ribosomes.;de Bethune M. P.;Eur. J. Biochem.,1978

5. The molecular basis of the inhibitory activities of type A and type B synergimycins and related antibiotics on ribosomes.;Di Giambattista M.;J. Antimicrob. Chemother.,1989

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