Variability of Inverted Repeats in All Available Genomes of Bacteria-Reference-Cited by-同舟云学术

Variability of Inverted Repeats in All Available Genomes of Bacteria

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Porubiaková Otília¹,Havlík Jan²,Indu ¹³,Šedý Michal⁴,Přepechalová Veronika¹⁴,Bartas Martin⁵,Bidula Stefan⁶,Šťastný Jiří²⁷,Fojta Miroslav¹,Brázda Václav¹⁴^ORCID

Affiliation:

1. Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic

2. Mendel University in Brno, Brno, Czech Republic

3. Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic

4. Brno University of Technology, Faculty of Chemistry, Brno, Czech Republic

5. Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic

6. School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, United Kingdom

7. Brno University of Technology, Faculty of Mechanical Engineering, Brno, Czech Republic

Abstract

Our manuscript reports for the first time a complete analysis of inverted repeats in all fully sequenced bacterial genomes. Thanks to the availability of unique computational resources, we were able to statistically evaluate the presence and localization of these important regulatory sequences in bacterial genomes. This work revealed a strong abundance of these sequences in regulatory regions and provides researchers with a valuable tool for their manipulation.

Funder

Czech Science Foundation

ERDF

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01648-23

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