Comparative Genomic Analysis Reveals Genetic Diversity and Pathogenic Potential of Haemophilus seminalis and Emended Description of Haemophilus seminalis

Author:

Chen Xiaowei1,Zhang Hanyun2,Feng Junhui1,Zhang Lei3,Zheng Minling4,Luo Haimin15,Zhuo Huiyan2,Xu Ning15,Zhang Xuan15,Chen Cha15ORCID,Qu Pinghua15ORCID,Li Youqiang2

Affiliation:

1. The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China

2. Department of Laboratory Medicine, The Affiliated Hexian Memorial Hospital of Southern Medical University, Guangzhou, China

3. Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou, China

4. Department of Clinical Laboratory, Guangdong Women and Children Hospital, Guangzhou, China

5. Department of Clinical Laboratory, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

Abstract

As a versatile opportunistic pathogen, the accurate identification of Haemophilus species is a challenge in clinical practice. In this study, we characterized the phenotypic and genotypic features of four H. seminalis strains that were isolated from human sputum specimens and propose the “ H . intermedius ” and hemin (X-factor)-independent H. haemolyticus isolates as belonging to H. seminalis .

Funder

National Science and Technology Fundamental Resources Investigation Program of China

Science and Technology Planning Project of Panyu District

Basic and Applied Research Project of Guangzhou Research Program of China

The Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine

Guangzhou Civil Affairs Bureau Planned Project of Science and Technology

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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