SARS-CoV-2 Infection of Microglia Elicits Proinflammatory Activation and Apoptotic Cell Death-Reference-Cited by-同舟云学术

SARS-CoV-2 Infection of Microglia Elicits Proinflammatory Activation and Apoptotic Cell Death

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Jeong Gi Uk¹,Lyu Jaemyun²,Kim Kyun-Do¹,Chung Young Cheul³,Yoon Gun Young¹,Lee Sumin¹,Hwang Insu¹,Shin Won-Ho³,Ko Junsu²,Lee June-Yong⁴⁵,Kwon Young-Chan¹^ORCID

Affiliation:

1. Center for Convergent Research for Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea

2. Arontier Co., Ltd., Seoul, Republic of Korea

3. Department of Predictive Toxicology, Korea Institute of Toxicology, Daejeon, Republic of Korea

4. Department of Microbiology and Immunology, College of Medicine, Yonsei University, Seoul, Republic of Korea

5. Institute for Immunology and Immunological Disease, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea

Abstract

Recent studies reported neurological and cognitive sequelae in patients with COVID-19 months after the viral infection with several symptoms, including ageusia, anosmia, asthenia, headache, and brain fog. Our conclusions raise awareness of COVID-19-related microglia-mediated neurological disorders to develop treatment strategies for the affected patients.

Funder

National Research Foundation of Korea

National Research Council of Science and Technology

Korea Institute of Toxicology

Yonsei University College of Medicine

Korea Health Industry Development Institute

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01091-22