Development of an <i>In Vitro</i> Model of the Gut Microbiota Enriched in Mucus-Adhering Bacteria-Reference-Cited by-同舟云学术

Development of an In Vitro Model of the Gut Microbiota Enriched in Mucus-Adhering Bacteria

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Calvigioni Marco¹^ORCID,Panattoni Adelaide¹,Biagini Francesco²³,Donati Leonardo¹,Mazzantini Diletta¹,Massimino Mariacristina¹,Daddi Costanza²³,Celandroni Francesco¹,Vozzi Giovanni²³,Ghelardi Emilia¹⁴^ORCID

Affiliation:

1. Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

2. Department of Information Engineering, University of Pisa, Pisa, Italy

3. Research Center “Enrico Piaggio”, University of Pisa, Pisa, Italy

4. Research Center “Nutraceuticals and Food for Health – Nutrafood”, University of Pisa, Pisa, Italy

Abstract

These findings highlight the importance of mucins in shaping intestinal microbial communities, even those in artificial gut microbiota systems. We propose our in vitro model based on mucin-coated electrospun gelatin structures as a valid device for studies evaluating the effects of exogenous factors (nutrients, probiotics, infectious agents, and drugs) on mucus-adhering microbial communities.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00336-23

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