Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents-Reference-Cited by-同舟云学术

Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Hishiki Takayuki¹,Morita Takeshi¹,Akazawa Daisuke¹,Ohashi Hirofumi¹,Park Eun-Sil²,Kataoka Michiyo³,Mifune Junki¹,Shionoya Kaho⁴⁵,Tsuchimoto Kana¹,Ojima Shinjiro¹,Azam Aa Haeruman¹,Nakajima Shogo⁴,Kawahara Madoka¹⁶,Yoshikawa Tomoki⁶,Shimojima Masayuki⁶,Kiga Kotaro¹,Maeda Ken²,Suzuki Tadaki³,Ebihara Hideki⁶,Takahashi Yoshimasa¹,Watashi Koichi¹⁴⁵⁷

Affiliation:

1. Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan

2. Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan

3. Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan

4. Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan

5. Department of Applied Biological Science, Tokyo University of Science, Noda, Japan

6. Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan

7. MIRAI, Japan Science and Technology Agency (JST), Saitama, Japan

Abstract

Mpox is a zoonotic disease caused by infection with the mpox virus, and a worldwide outbreak occurred in May 2022. The smallpox vaccine has recently been approved for clinical use against mpox in the United States.

Funder

Japan Agency for Medical Research and Development

MEXT | Japan Society for the Promotion of Science

MEXT | JST | JST-Mirai Program

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00566-23

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3. World Health Organization. 2022. Multi-country outbreak of monkeypox external situation report #3 - 10 August 2022. World Health Organization Geneva Switzerland. https://www.who.int/publications/m/item/multi-country-outbreak-of-monkeypox--external-situation-report--3---10-august-2022.

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5. Drug Development against Smallpox: Present and Future

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