In Vitro Activity of the Novel Antifungal Olorofim against Scedosporium and Lomentospora prolificans-Reference-Cited by-同舟云学术

In Vitro Activity of the Novel Antifungal Olorofim against Scedosporium and Lomentospora prolificans

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Georgacopoulos Ourania¹,Nunnally Natalie¹^ORCID,Law Derek²,Birch Mike²,Berkow Elizabeth L.¹,Lockhart Shawn R.¹^ORCID

Affiliation:

1. Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

2. F2G Ltd., Manchester, United Kingdom

Abstract

Scedosporium and Lomentospora infections are notoriously hard to treat as these organisms can be resistant to numerous antifungals. The manuscript contributes to our knowledge of the activity of the new antifungal agent olorofim and comparator agents against Lomentospora and against Scedosporium isolates that have been molecularly identified to the species level. The efficacy of olorofim against all species of Scedosporium and Lomentospora was confirmed.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02789-22

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