Role of the Two-Component System CiaRH in the Regulation of Efflux Pump SatAB and Its Correlation with Fluoroquinolone Susceptibility-Reference-Cited by-同舟云学术

Role of the Two-Component System CiaRH in the Regulation of Efflux Pump SatAB and Its Correlation with Fluoroquinolone Susceptibility

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Yang Xia¹²,Peng Wei¹²,Wang Ningning¹²,Dou Beibei¹²,Yang Fengming¹²,Chen Huanchun¹²,Yuan Fangyan³,Bei Weicheng¹⁴²⁵^ORCID

Affiliation:

1. State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China

2. The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan, China

3. Key Laboratory of Prevention and Control Agents for Animal Bacteriosis (Ministry of Agriculture), Institute of Animal Husbandry and Veterinary Sciences, Hubei Academy of Agricultural Sciences, Wuhan, China

4. Hubei Hongshan Laboratory, Wuhan, China

5. Guangxi Yangxiang Co., Ltd., Guigang, China

Abstract

Streptococcus suis is a zoonotic pathogen with high incidence and mortality rates in both swine and humans. Following antibiotic treatment, the organism has evolved many resistance mechanisms, among which efflux pump overexpression can promote drug extrusion from the cell.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Technical Innovation Project of Hubei Province

MOST | National Key Research and Development Program of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00417-22

Reference75 articles.