Six-Year Retrospective Analysis of Epidemiology, Risk Factors, and Antifungal Susceptibilities of Candidiasis from a Tertiary Care Hospital in South China

Author:

Bilal Hazrat1ORCID,Zhang Dongxing23,Shafiq Muhammad4ORCID,Khan Muhammad Nadeem5,chen Canhua6,Khan Sabir1,Wang Qian17,Cai Lin1,Islam Rehmat8,Hu Haibin9,Zeng Yuebin1ORCID

Affiliation:

1. Department of Dermatology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China

2. Department of Dermatology, Meizhou Dongshan Hospital, Meizhou, Guangdong Province, China

3. Department of Dermatology, Meizhou People’s Hospital, Meizhou, Guangdong Province, China

4. Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, China

5. Faculty of Biological Sciences, Department of Microbiology, Quaid-I-Azam University, Islamabad, Pakistan

6. Clinical Laboratory, Meizhou People's Hospital, Meizhou, Guangdong Province, China

7. Department of Medical-Surgical and Experimental Sciences, University of Sassari Neurology Unit, Azienza Ospedaliera Universitaria (AOU) Sassari, Italy

8. Key Laboratory of Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi’an, China

9. First Clinical Medical College, Guangdong Medical University, Zhanjiang, China

Abstract

This study provides important information on the burden of candidiasis, particularly candidemia, and the antifungal susceptibility of Candida species among hospitalized patients in an underdeveloped region of China. First, the finding that azoles were least effective against Candida species causing candidemia is particularly noteworthy, as it suggests the possibility of resistance to this class of antifungal agents.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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