The Impact of Bacterial Biofilms on End-Organ Disease and Mortality in Patients with Hematologic Malignancies Developing a Bloodstream Infection-Reference-Cited by-同舟云学术

The Impact of Bacterial Biofilms on End-Organ Disease and Mortality in Patients with Hematologic Malignancies Developing a Bloodstream Infection

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Di Domenico Enea Gino¹^ORCID,Marchesi Francesco²,Cavallo Ilaria¹,Toma Luigi³,Sivori Francesca¹,Papa Elena²,Spadea Antonio²,Cafarella Giuseppina²,Terrenato Irene⁴,Prignano Grazia¹,Pimpinelli Fulvia¹,Mastrofrancesco Arianna¹,D’Agosto Giovanna¹,Trento Elisabetta¹,Morrone Aldo⁵,Mengarelli Andrea²,Ensoli Fabrizio¹

Affiliation:

1. Microbiology and Virology, San Gallicano Dermatological Institute, IRCCS, Rome, Italy

2. Hematology and Stem Cell Transplant Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy

3. Department of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Rome, Italy

4. Biostatistics and Bioinformatic Unit, Scientific Direction, IRCCS Regina Elena National Cancer Institute, Rome, Italy

5. Scientific Direction, IRCCS San Gallicano Institute, Rome, Italy

Abstract

Bacterial bloodstream infection (BSI) is a significant complication in hematologic patients and is associated with high mortality rates. Despite improvements in BSI management, factors leading to sepsis are understood only partially.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00550-21

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